The life sciences were one of the first fields of study to adopt optical technologies with the invention of the microscope.  Shortly after as scientists were experimenting with ultraviolet light in an attempt to increase the resolution of biological microscopes, it was discovered that biological samples fluoresced.  Ever since then, fluorescence microscopy has become an invaluable tool in life sciences.  In addition to microscopy, fluoresce excitation is also used in flow cytometry for cell differentiation, DNA sequencing, and others.   Traditionally fluorescence applications utilize low noise TEM00 visible and ultraviolet lasers, but over the past few years, ultrafast mode-locked lasers for multi-photon excitation are becoming more and more popular.  Also, for the more traditional confocal fluorescence microscopes, confocal Raman microscopes are also becoming more popular in the life sciences.  Unlike fluorescence, which relies on fluorescent tags to differentiate between molecules or cells, Raman allows for the direct instigation of the molecular bond structure of the sample.  For confocal Raman microscopy in addition to being low noise and single spatial mode, the lasers must also be single frequency, and wavelength stabilized to ensure accurate spectral data.   

To learn more about the various laser applications in the lifesciences click on any of the applications listed below, or contact one of our laser experts today by calling 1-636-272-7222. 

Flow-Cytometry DNA Sequencing Confocal microscopy

Flow Cytometry


DNA Sequencing


Confocal Microscopy


multiphoton microscopy Optogenetics Fluorescience

Multi-Photon Microscopy




Fluorescence Lifetime


To see a full list of other applications RPMC lasers are used for please check out our applications page by clicking here.